

Key to the design was the goal of preserving similarity between the new and previously existing and successfully utilized fermenter hardware and software installations where feasible but implementing improvements where warranted and beneficial. In addition, the reasoning behind selection of some of these features has been included. Details of the design of these new fermenters and the new control system are described and compared with the existing installation for expected effectiveness. These systems were incorporated into an industrial research fermentation pilot plant, designed and constructed in the early 1980s.

A new PC/PLC-based control system also was implemented using GE Fanuc PLCs, Genius I/O blocks, and Fix Dynamics SCADA software.

Four new fermenters were designed and constructed for use in secondary metabolite cultivations, bioconversions, and enzyme production.
